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Going From Building AI to Running It
Most healthcare AI budgets fund building. Then the pilot succeeds, and query volume lands on the EHR, the claims platform, and an infrastructure budget nobody planned for. Drawing on Microsoft's Eduardo Kasner and the Silk webinar on AI inferencing, Frank Wang translates the six priorities for running AI into healthcare terms, explains why "more context" worsens the accuracy problem, and argues that isolation must happen at the workflow layer, not just the database.
By Weiran Yao
The pilot worked. Now the query volume belongs to your EHR, your claims platform, and your infrastructure budget. Here's what running AI in healthcare asks of the systems underneath it.
Most healthcare AI budgets fund building. A model bake-off, a prompt library, a pilot with 6 clinicians, a demo that lands with the CFO. Then the pilot succeeds, the workflow goes live, and the bill moves from the AI team to the infrastructure team. Nobody wrote that line item.
Silk and Microsoft ran a webinar on exactly this problem, titled AI Inferencing: Don't Break Your Architecture. Eduardo Kasner, Chief Data and AI Officer for Microsoft's high-tech sector, gave the cleanest definition I've heard. Training builds the brain. Inferencing is the brain at work, running semantic search, RAG, and agentic workflows against your live data. Kasner's argument is about databases. Ours is about what sits on top of them in healthcare, where the system of record has a 20-year uptime expectation and a compliance team attached.
Inference is the part that touches production
Every useful answer an agent gives starts with a lookup. Kasner calls this grounding, and it's the difference between a model that recites and a model that works. In healthcare, grounding means the member record, the claim history, the prior auth policy, the clinical note from last Tuesday.
So every step in an agentic workflow is a query somewhere. A prior auth agent that checks eligibility, pulls the guideline, reads the note, and drafts the determination has hit 4 systems before a human sees anything. Multiply that by every case in the queue and you've built a new class of database client that never sleeps and never batches.
The accuracy versus load trade
Kasner names a paradox worth pinning to the wall. To make the AI more accurate, you feed it more data, more context, and more complex queries. That load lands on production databases, the systems of record. Limit the data and the AI is fast but wrong. Give it everything and the system slows to a crawl or falls over.
Healthcare feels this harder than banking or e-commerce, because the accuracy bar is higher and the systems are older. Our own χ-BENCH testing found frontier agents complete only 28% of complex healthcare workflows. The reflex fix is more context. More context is the exact thing that loads the EHR. You can't prompt your way out of an architecture problem.
Three ways teams get the data wrong
Kasner sees organizations fall into the same traps when they try to feed data to AI. The first is the lakehouse pipe dream, where everything gets consolidated into one store that's elegant on the whiteboard and too slow and expensive in practice. The second is vector database sprawl, which adds layers of latency and an operational tax nobody budgeted.
The third is the default most teams land on, which is hitting production directly.
"The worst choice is blindly hitting production." Eduardo Kasner, Chief Data and AI Officer, High-Tech, Microsoft
Here's why that default is so dangerous. When a pilot fails, the load goes away. When a pilot succeeds, query volume doesn't grow, it multiplies. A workflow that ran 50 cases a week in the pilot runs the whole queue in production, and the EHR team finds out from a latency alert. In healthcare there's a second cost stacked on top. As we argued in The Data Tollbooth, you often pay the application vendor for access to your own data and then pay the inference vendor to reason over it. Blind production hits make both meters spin.
Six priorities, translated for healthcare
Kasner's list of what leadership has to get right is the right list. The healthcare column is ours.
| Priority | Kasner's point | What it means in healthcare |
|---|---|---|
| Accuracy | If the AI is wrong, users abandon the tool immediately. | A wrong eligibility answer becomes a denied claim or a delayed procedure. Clinicians give an agent one chance. |
| Data readiness | Models need the right context and parameters to be useful. | Context lives across the EHR, the claims platform, PDFs, and faxes. Readiness means knowing which system is authoritative for which field. |
| Performance | A few seconds of latency is a failure. | An agent that stalls inside a 15-minute visit or a call-center hold gets turned off by the people it was meant to help. |
| Privacy and security | Data sovereignty and compliance are non-negotiable. | PHI leaves the system of record the moment an agent reads it. Where it goes, who can see it, and what's logged has to be decided before the first query. |
| Scalability | AI usage patterns are wildly unpredictable. | Open enrollment, flu season, and a CMS deadline all arrive at once. The agent fleet has to scale without the EHR noticing. |
| Cost | Projects stall when infrastructure cost outpaces ROI. | Inference spend per workflow has to be visible before the pilot ends, or finance kills the rollout at the first surprise invoice. |
Isolation is the answer, at 2 layers
Kasner's prescription is isolation. AI development is iterative, which is a polite way of saying you'll break things, so give teams high-performance, isolated copies of production data to experiment against. Elastic scaling or instant environment duplication keeps the experiments off the systems the business runs on.
We'd push that one layer up. In healthcare, isolating the data isn't enough, because the thing that grows out of control is the workflow. The system of record should feed the agent and never own the job. We made that case in You Still Need Your System of Record, and running AI is where it bites.
In practice that looks like three habits. Run every agent inside a harness that reads from the system of record through governed connectors, so a runaway workflow throttles at the harness and never at the EHR. Simulate the workflow end to end before it sees production traffic, so you learn the 28% problem in a sandbox instead of a claims queue. Meter cost and latency per workflow from day one, so the CFO sees the inference bill before it becomes a surprise.
Building AI is a project. Running it is an operating discipline, and the architecture underneath decides whether the discipline is possible.
Where ACTAVA sits
ACTAVA KORA is the harness. Agents run inside it, read production data through governed connectors, and report cost and latency per workflow, so the load never lands blind on the system of record.
χ-BENCH is the isolated environment for testing. It simulates long-horizon healthcare workflows against realistic data before an agent touches a live queue.
ACTAVA COMPLIANCE governs what each agent can read, where PHI can travel, and what gets logged, which settles the privacy row in the table above before the first query runs.
CURA handles the healthcare-specific reasoning, so grounding pulls the right fields instead of the whole record.
Sources
- Silk, AI Inferencing: Don't Break Your Architecture, webinar with Tom O'Neill (Silk) and Eduardo Kasner (Microsoft)
- ACTAVA, χ-BENCH Update: Frontier Agents Complete Only 28% of Complex Healthcare Workflows
- ACTAVA, You Still Need Your System of Record. You Just Can't Let It Own Your Jobs to Be Done.
- ACTAVA, The Data Tollbooth
- Product pages: KORA, COMPLIANCE, χ-BENCH, CURA

Written by
Weiran Yao
CAIO & Co-Founder
AI research leader with deep expertise in large-scale model training, reasoning engines, and multi-agent systems. At Salesforce AI Research, Weiran led the post-training team behind the xLAM large action models, along with the Agentforce planning engine and the CodeGenie agent, and drove the pre-training of Salesforce's CoDA code diffusion model. He recently spearheaded open-source releases including Enterprise Deep Research, Webscale-RL, and CoDA-1.7B, advancing applied AI from research into production at enterprise scale. A CMU Ph.D. in Machine Learning, he has published 70+ papers, holds 13 U.S. patents, and serves on NeurIPS, ICML, ICLR, and ACL committees.


